Selecting a model system is usually one of the first and most challenging steps in exploring a clinical hypothesis, validating a technology, or understanding a biological process. Although cell lines have served the needs of biomedical research for decades, increasingly, grant and publication reviewers as well as agencies regulating drug development, are requesting researchers to reproduce their results in more representative or “clinically relevant” models. This webinar will introduce human and animal-derived primary cells and explain how they currently serve diverse biomedical clinical and research applications as biologically-relevant, species-specific, and simple to use biological systems.