The isolation of specific cell populations from blood products via immunomagnetic cell separation remains an integral operation in any research organization to enrich target cells for immunology and other fields in life sciences. AllCells offers a variety of cell types available for isolation.

Isolated Cell Types

CD34+ HSPCs

Hematopoietic stem and progenitor cells (HSPCs) are the key stem cell population in the bone marrow capable of self-renewal and multilineage differentiation into mature blood cell types. CD34+ HSPCs can be isolated from mobilized peripheral blood, bone marrow, and umbilical cord blood.

T Cells

T cells are the main effector cells of the adaptive immune system, characterized by the presence of a T cell receptor (TCR) on their cell surface. T cells recognize foreign antigens in the context of major histocompatibility complex molecules on antigen-presenting cells. There are three main types of T cells: cytotoxic, helper, and regulatory.

NK (Natural Killer) Cells

Natural killer (NK) cells are cytotoxic effectors of the innate immune system with a primary role in immunosurveillance. They are capable of mounting rapid immune responses against foreign pathogens and tumor cells. Primary CD56+ NK cells can be isolated from leukapheresis material (Leukopaks) via positive or negative immunomagnetic separation.

Monocytes

CD14+ monocytes are large agranular myeloid-derived leukocytes with roles in the inflammatory and anti-inflammatory processes of the innate immune response. They can differentiate into macrophages and dendritic cells (DC) responsible for phagocytosis, antigen presentation, and cytokine production.

B Cells

B cells are part of the adaptive immune system with a role in humoral immunity. B cells produce antibodies, function as antigen-presenting cells, and also secrete immunomodulatory cytokines. Primary CD19+ B cells can be isolated from leukapheresis (Leukopaks) via positive or negative immunomagnetic separation.

PBMCs (MNCs)

Peripheral blood mononuclear cells (PBMCs) consist of lymphocytes (T cells, B cells, and NK cells), monocytes, and dendritic cells, distinguished by the presence of a single round nuclei. Mononuclear cells are isolated from leukapheresis (Leukopaks) when high numbers of MNCs are required.

Donor Management System

AllCells® Matched Immune Cell Subsets


Discovery’s AllCells® Matched Immune Cell Subsets provide a consistent source of starting materials from a single donor, enabling well-controlled studies and the generation of high-quality, reliable data in CGT, immunotherapy, infectious disease, and vaccine development.

  • Matched CD3+ Pan T Cells & CD19+ B Cells
  • Matched CD3+ Pan T Cells & Mononuclear Cells (MNCs)
  • Matched CD4+ Helper T Cells & CD8+ Cytotoxic T Cells
  • Matched CD3+ Pan T Cells, CD56+ NK Cells, & MNCs

By removing donor variability, our ready-to-use cryopreserved matched subsets facilitate accurate evaluations of drug efficacy and safety, execution of co-culture and cytotoxicity studies, and in-depth investigations into immunomodulation, memory generation, and complex cellular interactions.

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Bulk Cell Isolations


AllCells offers bulk cell isolations of important cell types from single-donor leukapheresis and bone marrow material—standard and sequential immunomagnetic separation protocols are available. Obtain large quantities of quality-controlled cells including CD34+ HSPCs, lymphocyte populations (T cells, B cells, NK cells, and monocytes), and PBMCs for a variety of research and biomedical applications. Contact us for specific donor requests and custom isolation protocols.

Obtaining bulk quantities of highly pure and viable isolated cells from a qualified vendor offers researchers the opportunity to bank cells to support experimental consistency and comparability, and streamlines laboratory workflows.

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Outsource Cell Isolation

Save Time and Resources


Outsourcing the time-consuming process of isolating cells to an external supplier can streamline your lab’s workflow and liberate in-house personnel to focus on other priorities. Positive select and negative select isolations available.

Donor Management System

Diverse Donor Pool


Our proprietary Donor Management System (DMS) software and dedicated team takes a holistic, targeted approach to find the right donors for any program or timeline. Gain access to collections from donors with specific attributes to meet your project needs.

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Request a quote for your next order of high quality human primary cells.