Peripheral blood mononuclear cells (PBMCs) consist of lymphocytes (T cells, B cells, and NK cells), monocytes, and dendritic cells, distinguished by the presence of a single round nuclei. Mononuclear cells are isolated from leukapheresis (Leukopaks) when high numbers of MNCs are required. Cellular subpopulations (i.e., T cells) can be further isolated from mononuclear cells using immunomagnetic separation technologies.
Mononuclear cells are important medical research tools in a multitude of areas, including immunology, infectious diseases, disease modeling, biomarker identification, and personalized medicine.
Tissue source: Leukopak
AllCells offers fresh and cryopreserved MNCs derived from Leukopaks (PBMCs) in a variety of types and sizes. The product chart below provides detailed information on standard formats, anticoagulants and unit sizes for PBMCs. Don’t see what you’re looking for? Our Leukopak products can also be Made-to-order (MTO) with custom specifications to meet the specific requirements of your research project. For more information, please visit our MTO page or reach out to our Customer Success Team.
|Leukopaks||MNC||10M, 25M, 50M, 100M||100M, 300M, 2B, 4B, 7B|
MNCs (PBMCs) are isolated from Leukopaks treated with ammonium chloride to remove red blood cells (RBCs) and washed to remove platelets.
At AllCells, we believe that your success is our success. We believe that sharing our knowledge and expertise is more than a business practice, it’s a responsibility. And we believe that collaboration leads to better outcomes. Below is a collection of relevant links to PBMCs resouces including blog posts, webinars and useful protocols to help you become more efficient and more effective. Have technical questions about PBMCs products? Our Customer Success Team is standing by.
AllCells offers bulk cell isolations of important cell types from single-donor leukapheresis and bone marrow material—standard and sequential immunomagnetic separation protocols are available. Obtain large quantities of quality-controlled cells including CD34+ HSPCs, lymphocyte populations (T cells, B cells, NK cells, and monocytes), and PBMCs for a variety of research and biomedical applications. Contact us for specific donor requests and custom isolation protocols.
Obtaining bulk quantities of highly pure and viable isolated cells from a qualified vendor offers researchers the opportunity to bank cells to support experimental consistency and comparability, and streamlines laboratory workflows.