Hematopoietic stem and progenitor cells (HSPCs) are the key stem cell population in the bone marrow capable of self-renewal and multilineage differentiation into mature blood cell types. CD34+ HSPCs can be isolated from mobilized peripheral blood, bone marrow, and umbilical cord blood.
Clinical HSPC transplantation is used to treat blood cancers (leukemia, myeloma and lymphomas), autoimmune diseases, and more. Gene-modified HSPCs (in vivo or ex vivo) are a promising new modality for a growing number of human diseases including cancer, hemophilia A, beta-thalassemia, and sickle cell disease.
Tissue source: Mobilized Leukopak, Bone Marrow, Cord Blood
AllCells offers cryopreserved CD34+ cells derived from Mobilized Leukopaks, Bone Marrow, and Cord Blood in a variety of types and sizes. The product chart below provide detailed information on standard formats, anticoagulants and unit sizes for CD34+ cells. Don’t see what you’re looking for? Our Mobilized Leukopak and Bone Marrow products can also be Made-to-order (MTO) with custom specifications to meet the specific requirements of your research project. For more information, please visit our MTO page or reach out to our Customer Success Team.
|Mobilized Leukopak Reg F (Neupogen x 5 days)||Reg F CD34+, PS||0.5M, 1M, 5M, 10M, 25M||Bulk|
|Mobilized Leukopak Reg H (Neupogen x 5 days, Mozobil x 2 days)||Reg H CD34+, PS||1M, 5M, 10M, 25M||Bulk|
|Bone Marrow||CD34+ PS||0.5M, 1M, 2M, Bulk||Bulk|
|Cord Blood||CD34+ Single||1M||—|
|Cord Blood||CD34+ Mixed||1M||—|
Mobilized Leukopaks, Bone Marrow, Cord Blood
Isolated CD34+ HSCs are available from Mobilized Leukopaks, Bone Marrow, or Cord Blood. Positive immunomagnetic separation is used where CD34+ beads bind to target cells in the heterogeneous population - CD34+ cells remain bound to the beads while unwanted cells are removed. All our products are quality controlled for cell count and viability and are determined using a validated AO/PI protocol.
At AllCells, we believe that your success is our success. We believe that sharing our knowledge and expertise is more than a business practice, it’s a responsibility. And we believe that collaboration leads to better outcomes. Below is a collection of relevant links to CD34+ resouces including blog posts, webinars and useful protocols to help you become more efficient and more effective. Have technical questions about CD34+ products? Our Customer Success Team is standing by.
AllCells offers bulk cell isolations of important cell types from single-donor leukapheresis and bone marrow material—standard and sequential immunomagnetic separation protocols are available. Obtain large quantities of quality-controlled cells including CD34+ HSPCs, lymphocyte populations (T cells, B cells, NK cells, and monocytes), and PBMCs for a variety of research and biomedical applications. Contact us for specific donor requests and custom isolation protocols.
Obtaining bulk quantities of highly pure and viable isolated cells from a qualified vendor offers researchers the opportunity to bank cells to support experimental consistency and comparability, and streamlines laboratory workflows.