Mobilized Leukopaks are apheresis products collected from healthy donors treated with FDA-approved drugs to stimulate the migration of CD34+ hematopoietic stem and progenitor cells (HSPCs) from the bone marrow niche into the circulation. Mobilized peripheral blood, enriched in single-donor CD34+ HSPCs is collected through leukapheresis using the Spectra Optia® Apheresis System’s continuous flow centrifugal technology. The ease of collection and high yield of single-donor CD34+ cells is a major advantage to researchers to gain experimental consistency and scalability.
AllCells is the industry leader in supplying mobilized Leukopaks with the shortest lead time on the market. We have six different mobilization regimens available using G-CSF (Neupogen®), plerixafor (Mozobil®), or a combination of the two drugs as well as CD34+ cells isolated from mobilized Leukopaks.
AllCells can manufacture the following mobilized leukopak products:
Whole – blood bag collected from leukapheresis after mobilization
(HSC) CD34+ PS – Isolated cells positive for CD34. Phenotypically characteristic hematopoietic stem cells. Isolation by magnetic microbead positive selection.
Mobilized Leukopaks are apheresis products collected from healthy donors treated with approved drugs to stimulate mobilization of CD34+ hematopoietic stem and progenitor cells (HSPCs) from the bone marrow to the peripheral blood. This procedure results in large-scale yields of single-donor CD34+ HSPCs, allowing for scalability and reproducibility of experiments by limiting the impact of donor-to-donor variability. AllCells offers Mobilized Leukopaks with different mobilization regimens, including G-CSF (Neupogen®), plerixafor (Mozobil®), or a combination of the two drugs. Mobilized Leukopak products are offered either fresh or cryopreserved, and in different tissue formats*: Whole Mobilized Apheresis Tissue, CD34 Hematopoietic Stem and Progenitor Cells (HSPCs), Multiple Mobilization Regimens Available.
*Cell type, cell selection method, and unit size (by volume or cell count) vary depending on tissue format.
Additional Search Terms: mPB026-Reg.F, mPB018F, mPB015F, mPB016F, mPB017F, mPB009, Mobilized Leukopak
AllCells' on-site collection and processing facilities enables us to offer custom, made-to-order (MTO) products to meet the unique needs of our customers. From tissue collection to product shipment, AllCells’ experienced team of experts will help you define, design, and deliver your customized primary cell material.
We can accommodate specific donor requests, custom mobilization regimens requirements, bulk isolations, cryopreservation needs and more.
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