The simplicity and speed of immunomagnetic cell separation has made it the go-to method for isolating target cell populations since it was pioneered in 1990 by Miltenyi Biotec. The ability to isolate specific cell types from heterogeneous tissue or blood-derived sources such as whole peripheral blood, bone marrow, or cord blood is critical to advancing […]
Cell and gene therapies represent an expanding category of transformative medicines with the potential to change the way we treat human diseases. Broadly, these novel therapies include both in vivo and ex vivo strategies to modify target cells. Ex vivo therapies that involve isolating cells from a patient (autologous) or a donor (allogeneic) and modifying […]
Primary cells, such as those isolated from the bone marrow or peripheral blood, are important for a wide scope of research and clinical applications – from studying molecular mechanisms driving disease progression, to developing ex vivo therapies in regenerative medicine. Unlike immortalized cell lines, primary cells have a finite lifespan in culture and can undergo unwanted changes like genetic drift and […]
The immune system is our body’s biological defense system against a variety of pathogens and is separated into the innate and adaptive branches. Our innate immune system is the body’s first line of defense, activating immediately or within hours of a foreign antigen’s appearance in the body with natural killer (NK) cells playing a key […]
