In the past decade, emerging therapeutic modalities like cell and gene therapies have opened up new treatment options for previously intractable diseases, changing the industry needs for primary tissues. While autologous therapies—which are created using a patient’s own cells—still dominate the field, many cell and gene developers are investing in allogeneic therapies that can be […]
What are Monocytes? Hematopoietic stem cells (HSCs), which reside in the bone marrow give rise to blood cells in a process called hematopoiesis. HSCs differentiate into the lymphoid and myeloid lineages, which further differentiate into mature blood cell types (Figure 1). Monocytes are large agranular leukocytes of the myeloid lineage comprising between 5% – 10% […]
What are PBMCs? Human peripheral blood mononuclear cells (PBMCs) are key components of the body’s complex and dynamic immune system. A mononuclear cell is characterized by a single round nucleus and includes lymphocytes, monocytes, and dendritic cells. These cells have important immunological roles defending the body from infection, cancer, and other foreign invaders, making them […]
